Secretome Therapeutics, a clinical-stage biotechnology company developing innovative therapies from neonatal cardiac progenitor cells (nCPCs), announced today that the first patient has been dosed in its Phase 1 clinical trial of STM-01 for heart failure with preserved ejection fraction (HFpEF).
This marks the first-ever clinical study of an allogeneic, off-the-shelf stem cell therapy for HFpEF, a leading global cause of hospitalization, morbidity, and mortality. In the U.S. alone, approximately 6.7 million adults live with heart failure, with HFpEF accounting for at least half of these cases.